The treatment is not that painful. You will be expected to feel a tingling ‘pins and needles’ sensation at the treatment site. Most dermatology departments are able to offer a trial of the treatment through a nurse-led clinic. This enables you to see if the treatment works successfully before you purchase your own iontophoresis machine for home use. The treatment then can be can be carried out in the privacy of your own home without needing any medical supervision or anyone to operate the machine for you. You can find various iontophoresis machine suppliers online.