Hidrex GS 400 Review


Hidrex GS 400 is one of the most well known models of iontophoresis device used by hyperhidrosis patients.

Pros: Professional quality, good built, sturdy, portable, choice of power modes

Cons: Pricey


The Hidrex GS 400 is a mains powered, Direct current iontophoresis device.

Body Areas
  • Palmar (Palms)
  • Plantar (Feer)
  • Axillary (underarm)
Out of box
  • 1 x Hidrex GS 400 contol unit.
  • 1 x Electrode plates for treatment.
  • 1 x Pair of 4mm electrode connection cables.
  • 1 x AC 110v – 240v power adapter.
  • 1 x Combined carry case & treatment tubs.
  • Manufacturer 2 year warranty on control unit.

Click here to see options and buy Hidrex GS 400 (worldwide shipping available)


See the reviews of Hidrex GS 400 below

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Hidrex GS 400
Average rating:  
 8 reviews
by Al Abaya Sison on Hidrex GS 400
What I like in this machine

I used this machine for treating my excessive sweating of varies areas of my body. There are several things that I liked in this machine over the other. First, Hidrex GS 400 device is easy to operate, treatment is simple to set up and administer. The device features automatic detection. For example, when you place your hands inside the treatment trays, your therapy begins by slowly building up the current, and at the end of the session it will decrease the current slowly back down to zero.

Next is that no batteries required to use this. It is a professional electronic device you plug in to a normal outlet.

Also with a direct current, adjustable from 1 to 60 volts (in 1 Volt increments), @ 30 mA, I got the most effective treatment amperage and voltage for stopping my sweating. Also, the Hidrex DC has a memory function that remembers the last settings I used.

As for the results, I am having quite good one, I have had it 15 days and have done 12, 15 minute sessions for Hands and feet this gave me 95% improvement on hands, the feet I may need to go higher voltage or longer time as they are about 80% improved. I missed a day out to see if it had stopped the sweating properly and it did so I will continue to do a treatment then miss 2 days and so on to hopefully having to do it only once per week.

by John B. on Hidrex GS 400
Hidrex GS 400 - my review

I am very happy with this iontophoresis machine, especially because it's portable and practical. I often have a hectic schedule, so it would be near impossible to keep up with iontophoresis if this wasn't portable.

Having said that, I must add that while this device works very well on hands and feet, I cannot use it on underarms. I bought a special Hidrex applicator for underarms, but with this machine, it either hurts or isn't effective. But it's okay, since my underarms sweating isn't that bad to begin with. What matters is that Hidrex works perfectly on my hands and feet - I now only sweat when I skip maintenance iontophoresis treatments, which is very, very rare. Thumbs up!

by Karen on Hidrex GS 400
Took a month of experimenting to get good results


It's great having this kind of device in my own home, so I can have treatments whenever I want. The machine is of professional quality and so are the results. My feet sweating is now almost completely gone.


There are no universal settings - everyone needs to experiment before finding the right voltage. I started with 30 volts, it was too strong, then I switched to 15 volts, and finally settled at about 20 to get good results without hurting my skin. It took me about a month to get into a routine and that's when results started showing.

Overall, Hidrex GS 400 takes some patience, but pays off eventually.

by Nikki R. on Hidrex GS 400
The best choice for me

Hidrex is my favorite iontophoresis brand: I tried out various devices in several hospitals over the years (mostly Fischer), and somehow Hidrex treatments felt best, less rough I suppose. Now I finally bought one for myself, and so far all seems good.

The fact iontophoresis doesn't hurt a bit means that I can set the current intensity higher. Probably thanks to this, my results with Hidrex are better than any other results in the past! It also helps that now I have the device at home so I can easily adhere to the schedule.

I'm a little worried because warranty only covers 2 years, and considering the price, I hope this will last me at least 5-6 years!

by Michael Hollander on Hidrex GS 400
Sucessfully Treated Palmar & Plantar HH

This reduced my sweating, but to maintain the dryness I need to take 2 palmar treatments a week, and 1 plantar treatment a week. It takes a lot of time... Otherwise, I'm happy with this.

What I liked:

- Reliable manufacturer and obvious professional quality

- Cool control unit with many features

- Good price (at least when compared to other high-end devices!)

- Painless, non-invasive and effective

What I didn't like:

- I can't take the hand & feet treatments at the same time, because I don't have an extra pair of trays... But even if I had them I probably wouldn't be able to use them.) So far, my hands couldn't take the higher current which I use for my feet.)

by Mick Charwall on Hidrex GS 400
Stops my feet from sweating

Unlike the reviewer who found this painful, I have rather thick skin on my feet, which is probably because I often run barefoot on a sandy beach near my home. (This is also a great way to run without being annoyed by wet sneakers.)

A fair amount of research told me I will probably need intense treatments, but just to be sure I tried out my friend's Hidrex PS 500. As it turned out, I required nearly 100% pulse-width to feel even the slightest flow of current, so I decided to save up by buying a direct current Hidrex.

The current can be harsh on the upper part of the feet, but I simply apply Vaseline on that area – this solves the problem.

I don't use the device regularly, but when I do, it usually takes only about 5 treatments in a week and I'm already sweating less. I'm sure my shoes are even more thankful than I am!

by Christina Freicht on Hidrex GS 400

This was bad - I had Hidrex GS 400 for less than a month before I gave it up because I couldn't set the current (voltage) to work for me.

If I did treatments with very low settings, it wasn't painful, but these treatments were ineffective and my feet and hands still sweated afterwards. Maybe there was a small decrease of sweating in only a tiny portion of my feet, but that was not nearly as good as iontophoresis should be.

I couldn't use a stronger current because with higher settings the sensation was very unpleasant and sometimes even painful. I could only hold out for about 5 minutes per session, and that wasn't enough for it to work.

At the end I talked to Hidrex customer service - I must say they were very helpful - and negotiated to return this model, pay the difference in price and get Hidrex PSP 1000. It cost me nearly twice as much but was worth it, because it seems that I have very sensitive skin and direct current devices are not effective for me!

by Brittany Davidson on Hidrex GS 400
Not for sensitive skin, but otherwise great

Using Hidrex GS 400 was a big relief for me in one way: I didn't have to worry about batteries anymore. This is something my old device used, and in the long run it turned out to be annoying. So, I wasn't sorry to pay more for Hidrex, although the ideal price should be lower.

About the treatments: I am using Hidrex GS 400 on my feet with complete success. My usual settings include 20V and 25 minutes of soaking, and I apply a bit of petroleum jelly on my feet above water level. Hidrex got my feet dry, so I'm happy. I use it for maintenance every 10 days and it's enough.

Unfortunately, with underarms I didn't have that much success. It seems that my armpit skin is pretty sensitive, so it always gets red and irritated in the area where I use iontophoresis sponges. I tried lowering the current intensity, but while it removed the irritation, it also halved the effectiveness of treatments - my underarms would still partially sweat afterwards.

In short: Hidrex is easy-to-use, reliable and altogether a good choice for plantar hyperhidrosis, but I wouldn't recommend it for axillary hyperhidrosis.


About Author

I have had hyperhidrosis (palms and feet) since my childhood. I have tried/researched almost every treatment for hyperhidrosis over last decade, and in the process have acquired considerable experience that I hope will help others suffering with hyperhidrosis. I am happy to help you in whatever way I can to manage your excessive sweat problem - see the About page for more details and my contact information. Remember you are not alone, and that hyperhidrosis is entirely manageable with informed treatment. Good luck! PS: I recently published all that I have learnt about Hyperhidrosis in my book No Sweat! I encourage you to check that out as I believe its the best resource out there to understand and manage hyperhidrosis without falling for the miracle cures. Will love to hear your feedback on how to make it better.

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